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Millipore/04-1074 | Anti-PECAM-1 [CD31] Antibody, clone EP3095, rabbit monoclonal/04-1074/100 µL,Millipore,,Millipore,密理博,merckmillipore,Millipore美元价/进货价 美国密理博公司,,Array.Array.Array蚂蚁淘厂家直采.
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℡ 4000-520-616
℡ 4000-520-616
Millipore/04-1074 | Anti-PECAM-1 [CD31] Antibody, clone EP3095, rabbit monoclonal/04-1074/100 µL
产品编号:04-1074
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场      地:美国(厂家直采)
产品分类: 抗体类>一抗>功能性抗体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:待定
品      牌: Millipore
公      司:Millipore
公司分类:
Millipore/04-1074 | Anti-PECAM-1 [CD31] Antibody, clone EP3095, rabbit monoclonal/04-1074/100 µL
商品介绍
Description
CatalogueNumber04-1074
DescriptionAnti-PECAM-1[CD31]Antibody,cloneEP3095,rabbitmonoclonal
AlternateNames
  • CD31antigen
  • PECAM-1
  • CD31/EndoCAM,adhesionmolecule
BackgroundInformationCD31,alsoknownasplateletendothelialcelladhesionmolecule1(PECAM1)isatypeIintegralmembraneglycoprotein,andamemberoftheimmunoglobulinsuperfamilyofcellsurfacereceptors.PECAM-1isconstitutivelyexpressedonthesurfaceofendothelialcellswhereitisconcentratedatcelljunctions.PECAM-1isalsoexpressedatlowlevelsonallleukocytesandplatelets.HomotypicinteractionofCD31isimportantincell-cellinteraction,cell-matrixinteractionandsignaltransduction.
ProductInformation
FormatUnpurified
Control
  • THP-1andJurkatcelllysates
PresentationRabbitMonoclonalinbuffercontaining50mMTris-Glycine(pH7.4),0.15MNaClcontaining40%Glycerol,0.01%sodiumazideand0.05%BSA.
StorageandShippingInformation
StorageConditionsStablefor1yearat-20ºCfromdateofreceipt.
HandlingRecommendations:Uponreceipt,andpriortoremovingthecap,centrifugethevialandgentlymixthesolution.Aliquotintomicrocentrifugetubesandstoreat-20°C.Avoidrepeatedfreeze/thawcycles,whichmaydamageIgGandaffectproductperformance.Note:VariABIlityinfreezertemperaturesbelow-20°Cmaycauseglycerolcontainingsolutionstobecomefrozenduringstorage.
Applications
ApplicationPleasenotethatthisproductwillnotbeavailableforsaleafterMarch15,2015.Pleaseselectoneoftheotherantibodiesagainstthistarget.Anti-PECAM-1[CD31]Antibody,cloneEP3095,RabbitdetectslevelofPECAM-1[CD31]&hasbeenpublished&validatedforuseinWB,IH(P),FC.
KeyApplications
  • WesternBlotting
  • Immunohistochemistry(Paraffin)
  • FlowCytometry
ApplicationNotesImmunohistochemistryAnalysis:1:250-500dilutionfromapreviouslotdetectedPECAM1inhumanuterusandtonsiltissue.

FlowCytometry:1:70dilutionfromapreviouslotwasusedonFC.
BIOLOGicalInformation
ImmunogenSyntheticpeptidecorrespondingtoresiduesonhumanPECAM-1.
CloneEP3095
HostRabbit
SpecificityThisantibodyrecognizesPECAM1.
IsotypeIgG
SpeciesReactivity
  • Human
AntibodyTypeMonoclonalAntibody
EntrezGeneNumber
GeneSymbol
  • CD31
  • CD31/EndoCAM
  • EndoCAM
  • GPIIA
  • PECAM-1
PurificationMethodUnpurified
UniProtNumber
UniProtSummaryFUNCTION:Thisproteinisacelladhesionmoleculeexpressedonplateletsandatendothelialcellintercellularjunctions.

SUBCELLULARLOCATION:Membrane;Single-passtypeImembraneprotein.

TISSUESPECIFICITY:Longisoformpredominatesalltissuesexamined,isoformDelta12wasdetectedonlyintracheaandisoformDelta14-15onlyinlung,isoformDelta14wasdetectedinalltissuesexaminedwiththestrongestexpressioninheart.

PTM:PhosphorylatedonSerandTyrresiduesaftercellularactivation.

SEQUENCESIMILARITIES:Contains6Ig-likeC2-type(immunoglobulin-like)domains.

MolecularWeight130kDa
PhysicochemicalInformation
Dimensions
MaterialsInformation
MaterialsInformation
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