产品编号：FCABS165A6
市 场 价：¥5340.00
场 地：美国(厂家直采)
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商品介绍
| Description | |
|---|---|
| CatalogueNumber | FCABS165A6 |
| TradeName |
|
| Description | Milli-Mark™Anti-MAPK1/2(tERK)Antibody,AlexaFluor647Conjugate |
| AlternateNames |
|
| BackgroundInformation | Theextracellularsignal-regulatedkinases1and2(ERK1andERK2),alsocalledMAPK1andMAPK2,aremembersoftheMitogenActivatedProteinKinase(MAPK)familyofproteinsfoundinalleukaryotes.Becausethe44kDaERK1andthe42kDaERK2arehighlyhomologousandbothfunctioninthesameproteinkinasecascade,thetwoproteinsareoftenreferredtocollectivelyasERK1/2orMAPK1/2.TheMAPK1/2signalingcascadehasbeenshowntobeacriticalregulatorofcelldifferentiation,cellphysiologyandneuronalfunction.AberrantcontrolofMAPK1/2activityhasbeenimplicatedinavarietyofpathologicalconditions,includingcancerandautoimmunediseases,andefficientstudymethodsareindemand. |
| ProductInformation | |
|---|---|
| Format | AlexaFluor®647 |
| Control |
|
| Presentation | PurifiedrabbitpolyclonalantibodyconjugatedtoAlexaFluor647inPBSbufferwith15mg/mLBSAand0.1%SodiumAzide |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Maintainedrefrigeratedat2-8°Cfromdateofreceipt.Protectedfromlightinundilutedaliquotsfor6monthsfromdateofreceipt. |
| Applications | |
|---|---|
| Application | Milli-MarkAnti-MAPK1/2(tERK)Antibody,AlexaFluor647ConjugatedetectslevelofMAPK1/2(tERK)&hasbeenpublished&validatedforuseinFC. |
| KeyApplications |
|
| BIOLOGicalInformation | |
|---|---|
| Immunogen | KLH-conjugatedlinearpeptidecorrespondingtoratMAPK1/2attheC-terminus. |
| Epitope | C-terminus |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Rabbit |
| Specificity | AntibodyrecognizesMAPK1/2.C-terminus. |
| SpeciesReactivity |
|
| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| EntrezGeneSummary | Kinaseinvolvedinintracellularsignalling;componentofMapksignallingpathway[RGD] |
| GeneSymbol |
|
| PurificationMethod | ProteinAPurfied |
| UniProtNumber | |
| UniProtSummary | FUNCTION:Involvedinboththeinitiationandregulationofmeiosis,mitosis,andpostmitoticfunctionsindifferentiatedcellsbyphosphorylatinganumberoftranscriptionfactorssuchasELK-1.PhosphorylatesEIF4EBP1;requiredforinitiationoftranslation.Phosphorylatesmicrotubule-associatedprotein2(MAP2).PhosphorylatesSPZ1.Phosphorylatesheatshockfactorprotein4(HSF4)Bysimilarity |
| MolecularWeight | 43kDaCalculated |
| PhysicochemicalInformation |
|---|
| Dimensions |
|---|
| MaterialsInformation |
|---|
| MaterialsInformation |
|---|
品牌介绍
Millipore常用产品报价单
| 产品名 | 货号 | 公司分类 | 商城分类 | 美金价 |
| Millipore/475855-1R神奇滤布 密理博Millipore现货促销 | 475855-1R | Life Science Research | 膜 | 93.50 | Millipore/17-701/EZ-Magna RIP™ RNA-Binding Protein Immunoprecipitation Kit | 17-701 | Life Science Research | 定量试剂盒 | 653.00 | Millipore/RIPAb+ Ago2 - RIP Validated Antibody and Primer Set | 03-110 | Life Science Research | 抗体套装 | 433.00 | Millipore/CBL468F | Anti-PECAM-1 Antibody, clone HC1/6, FITC conjugated/CBL468F/100 assays | CBL468F | Antibodies and Assays | 功能性抗体 | 298.00 | Millipore/ECM460 | αVβ3/PECAM Investigator Kit/ECM460/1 kit | ECM460 | Antibodies and Assays | 夹心法ELISA | 477.00 |
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