商品介绍
| Description | |
|---|---|
| CatalogueNumber | AB2261 |
| Description | Anti-Tbr1Antibody |
| AlternateNames |
|
| BackgroundInformation | Tbr1geneisamemberofaconservedfamilyofgenesthatshareacommonDNA-bindingdomain,theT-box.T-boxgenesencodetranscriptionfactorsinvolvedintheregulationofdevelopmentalprocesses.Tbr1,aputativetranscriptionfactorknowntobeexpressedinpost-mitoticneurons,hasbeenfoundhighlyexpressedinglutamatergicearly-borncorticalneurons.Asimilarproteinhasbeendisruptedinmiceandshowntobecriticalforearlycorticaldevelopment,andcauseslossofprojectionneuronsintheolfactorybulbsandolfactorycortex.TheC-terminalregiontheTbr1derivedproteinwasfoundtobenecessaryandsufficientforassociationwiththeguanylatekinasedomainofcalcium/calmodulin-dependentserineproteinkinase. |
| ProductInformation | |
|---|---|
| Format | AffinityPurified |
| Control |
|
| Presentation | Purifiedchickenpolyclonalinbuffercontaining0.1MTris-Glycine(pH7.4,150mMNaCl)with0.05%sodiumazide. |
| StorageandShippingInformation | |
|---|---|
| StorageConditions | Stablefor1yearat2-8°Cfromdateofreceipt. |
| BIOLOGicalInformation | |
|---|---|
| Immunogen | KLH-conjugatedlinearpeptidecorrespondingtomouseTbr1. |
| Epitope | Internal |
| Concentration | PleaserefertotheCertificateofAnalysisforthelot-specificconcentration. |
| Host | Chicken |
| Specificity | ThisantibodyrecognizesTbr1. |
| SpeciesReactivity |
|
| SpeciesReactivityNote | Proventoreactwithhuman,mouse,andrat.Predictedtoreactwithhorse,pig,opossum,bovine,andcaninebasedon100%sequencehomology. |
| AntibodyType | PolyclonalAntibody |
| EntrezGeneNumber | |
| GeneSymbol |
|
| PurificationMethod | AffinityPurfied |
| UniProtNumber | |
| UniProtSummary | FUNCTION:Probabletranscriptionalregulatorinvolvedindevelopmentalprocesses.TBR1isrequiredfornormalbraindevelopment. SUBCELLULARLOCATION:NucleusPotential. TISSUESPECIFICTY:Expressedinspecificlaminainthedevelopingandadultbrain. DEVELOPMENTALSTAGE:Firstdetectedaroundday10ofembryonicdevelopmentinthepreplate,atday12.5,inthecorticalplateandintermediatezone,andfromday16.5to18.5,inarostro-caudalgrADIentinthesubplate.Inthethalamus,expressionisfirstobservedatpostnatalstage,P7,andweakexpressioncontinuesinlaterpostnatalandadultstages. SEQUENCESIMILARITIES:Contains1T-boxDNA-bindingdomain. |
| MolecularWeight | ~68kDaisobserved;however,UniProtKB/Swiss-ProtentryQ64336(TBR1_MOUSE)listsamassof73.941kDa. |
| PhysicochemicalInformation |
|---|
| Dimensions |
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| MaterialsInformation |
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| MaterialsInformation |
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品牌介绍
Millipore常用产品报价单
| 产品名 | 货号 | 公司分类 | 商城分类 | 美金价 |
| Millipore/475855-1R神奇滤布 密理博Millipore现货促销 | 475855-1R | Life Science Research | 膜 | 93.50 | Millipore/17-701/EZ-Magna RIP™ RNA-Binding Protein Immunoprecipitation Kit | 17-701 | Life Science Research | 定量试剂盒 | 653.00 | Millipore/RIPAb+ Ago2 - RIP Validated Antibody and Primer Set | 03-110 | Life Science Research | 抗体套装 | 433.00 | Millipore/CBL468F | Anti-PECAM-1 Antibody, clone HC1/6, FITC conjugated/CBL468F/100 assays | CBL468F | Antibodies and Assays | 功能性抗体 | 298.00 | Millipore/ECM460 | αVβ3/PECAM Investigator Kit/ECM460/1 kit | ECM460 | Antibodies and Assays | 夹心法ELISA | 477.00 |
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