Description | |
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Overview | Acell-permeableoxobutananilidecompoundthatispredictedtointeractwithGlut(GlucoseTransporter)atanintracellularsitebasedonavirtualdockingstudyandshowntoinhibitGlut-mediatedcellularglucoseuptake(50%and80%inhibitionof2-deoxy-D-glucoseuptakeinGlut1-andGlut4-overexpressingL6myoblasts,respectively,at300µM).Fas-resistantcelllinesthataremadeFas-responsiveuponmediumglucosedeprivationarealsoshowntobesensitizedbyFasentintoFas-mediatedcelldeath(ED50=35µMinPPC-1cultures),whilecellsthatremainFas-resistantuponglucosedeprivation,e.g.DU145,areshownnottobesensitizedbyFasentintoFas-mediateddeath. |
CatalogueNumber | 341305 |
BrandFamily | Calbiochem® |
Synonyms | GlucoseTransporterInhibitor,6094911,N-(4-Chloro-3-(trifluoromethyl)phenyl)-3-oxobutanamide |
ProductInformation | |
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CASnumber | 392721-37-8 |
Form | Off-whitesolid |
HillFormula | C₁₁H₉ClF₃NO₂ |
Chemicalformula | C₁₁H₉ClF₃NO₂ |
StructureformulaImage |
StorageandShippingInformation | |
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ShipCode | AmbientTemperatureOnly |
Toxicity | StandardHandling |
Storage | +2°Cto+8°C |
ProtectfromLight | Protectfromlight |
Donotfreeze | Oktofreeze |
SpecialInstructions | Followingreconstitution,aliquotandfreeze(-20°C).Stocksolutionsarestableforupto3monthsat-2°C. |
Applications |
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BIOLOGicalInformation | |
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Purity | ≥95%byHPLC |
PhysicochemicalInformation |
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Dimensions |
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MaterialsInformation |
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MaterialsInformation |
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Millipore常用产品报价单
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Millipore/475855-1R神奇滤布 密理博Millipore现货促销 | 475855-1R | Life Science Research | 膜 | 93.50 | Millipore/17-701/EZ-Magna RIP™ RNA-Binding Protein Immunoprecipitation Kit | 17-701 | Life Science Research | 定量试剂盒 | 653.00 | Millipore/RIPAb+ Ago2 - RIP Validated Antibody and Primer Set | 03-110 | Life Science Research | 抗体套装 | 433.00 | Millipore/CBL468F | Anti-PECAM-1 Antibody, clone HC1/6, FITC conjugated/CBL468F/100 assays | CBL468F | Antibodies and Assays | 功能性抗体 | 298.00 | Millipore/ECM460 | αVβ3/PECAM Investigator Kit/ECM460/1 kit | ECM460 | Antibodies and Assays | 夹心法ELISA | 477.00 |