Description | |
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Overview | Acell-permeableN-methylatedanalogofGSK-3InhibitorIX,BIO(Cat.No.361550)thatservesasarelevantkinaseinactivecontrol(IC50>92µMforCdk1/B,>100µMforCdk5/p25,andGSK-3α/β).Actsasapotentligandforarylhydrocarbonreceptor(AhR;EC50=20nMand93nMforyeastandhepatomareportersystems,respectively)anddisplaysantiproliferativeproperties. |
CatalogueNumber | 361556 |
BrandFamily | Calbiochem® |
Synonyms | 1-Methyl-BIO |
ProductInformation | |
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CASnumber | 710323-61-8 |
ATPCompetitive | N |
Form | Darkredsolid |
HillFormula | C₁₇H₁₂BrN₃O₂ |
Chemicalformula | C₁₇H₁₂BrN₃O₂ |
ReversIBLe | N |
StructureformulaImage |
StorageandShippingInformation | |
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ShipCode | AmbientTemperatureOnly |
Toxicity | StandardHandling |
Storage | +2°Cto+8°C |
ProtectfromLight | Protectfromlight |
Donotfreeze | Oktofreeze |
SpecialInstructions | Followingreconstitution,aliquotandfreeze(-20°C).Stocksolutionsarestableforupto6monthsat-20°C. |
Applications |
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BIOLOGicalInformation | |
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PrimaryTarget | Relevantkinaseinactivecontrol |
PrimaryTargetIC<sub>50</sub> | >92µMforCdk1/B,>100µMforCdk5/p25,andGSK-3α/β |
Purity | ≥97%byHPLC |
PhysicochemicalInformation | |
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Cellpermeable | Y |
Dimensions |
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MaterialsInformation |
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MaterialsInformation |
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