商品介绍
| Description | |
|---|---|
| CatalogueNumber | 14-155 |
| BrandFamily | Upstate |
| TradeName |
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| Description | HistoneH1Protein,20mg |
| AlternateNames |
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| BackgroundInformation | H1andrelatedlinkerhistonesareimportantbothformaintenanceofhigher-orderchromatinstructureandfortheregulationofgeneexpression.NucleosomalstABIlizationisprovidedthroughthebindingofhistoneH1tothenucleosomaldyadandthelinkerDNAenteringandexitingthecoreparticle.AdditionalexperimentalevidenceillustratestheinfluenceofhistoneH1onchromatinarrangementandcompaction.ThefamilyofhistoneH1proteinscontainsfivesomaticvariants(H1.1,H1.2,H1.3,H1.4andH1.5)whichareexpressedinnearlyallcelltypes. |
| ProductInformation |
|---|
| StorageandShippingInformation | |
|---|---|
| StorageConditions | 1yearat-20°C |
| Applications | |
|---|---|
| Application | PurifiedbovineHistoneH1proteinforuseasasubstrateinhistonemodificationassays(HAT,HDAC,DNMT)andchromatinassemblystudies. |
| KeyApplications |
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| BIOLOGicalInformation | |
|---|---|
| Source | Lysinerichfractionfromcalfthymus |
| SpecificActivity | ForSpecificActivitydata,refertotheCertificateofAnalysisforindividuallotsofthisenzyme. |
| EntrezGeneNumber | |
| EntrezGeneSummary | HistonesarebasicnuclearproteinsresponsIBLefornucleosomestructureofthechromosomalfiberineukaryotes.Twomoleculesofeachofthefourcorehistones(H2A,H2B,H3,andH4)formanoctamer,aroundwhichapproximately146bpofDNAiswrappedinrepeatingunits,callednucleosomes.Thelinkerhistone,H1,interactswithlinkerDNAbetweennucleosomesandfunctionsinthecompactionofchromatinintohigherorderstructures.ThisgeneisintronlessandencodesamemberofthehistoneH1family.TranscriptsfromthisgenelackpolyAtailsbutinsteadcontainapalindromicterminationelement.Thisgeneisfoundinthelargehistonegeneclusteronchromosome6. |
| GeneSymbol |
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| PurificationMethod | Sterilizedthrougha0.2micronmembranefilter |
| UniProtNumber | |
| UniProtSummary | FUNCTION:SwissProt:P10412#HistonesH1arenecessaryforthecondensationofnucleosomechainsintohigherorderstructures. SIZE:219aminoacids;21865Da SUBCELLULARLOCATION:Nucleus. SIMILARITY:SwissProt:P10412##BelongstothehistoneH1/H5family. MISCELLANEOUS:Thisvariantaccountsfor60%ofhistoneH1. |
| MolecularWeight | 32kDa |
| PhysicochemicalInformation |
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| Dimensions |
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| MaterialsInformation |
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| MaterialsInformation |
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品牌介绍
Millipore常用产品报价单
| 产品名 | 货号 | 公司分类 | 商城分类 | 美金价 |
| Millipore/475855-1R神奇滤布 密理博Millipore现货促销 | 475855-1R | Life Science Research | 膜 | 93.50 | Millipore/17-701/EZ-Magna RIP™ RNA-Binding Protein Immunoprecipitation Kit | 17-701 | Life Science Research | 定量试剂盒 | 653.00 | Millipore/RIPAb+ Ago2 - RIP Validated Antibody and Primer Set | 03-110 | Life Science Research | 抗体套装 | 433.00 | Millipore/CBL468F | Anti-PECAM-1 Antibody, clone HC1/6, FITC conjugated/CBL468F/100 assays | CBL468F | Antibodies and Assays | 功能性抗体 | 298.00 | Millipore/ECM460 | αVβ3/PECAM Investigator Kit/ECM460/1 kit | ECM460 | Antibodies and Assays | 夹心法ELISA | 477.00 |
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